GO.ID Term Annotated Significant Expected classicFisher gray.1 GO:0003823 antigen binding 55 6 0.77 0.00011 gray.2 GO:0001664 G-protein coupled receptor binding 176 10 2.48 0.00018 gray.3 GO:0005125 cytokine activity 146 9 2.05 0.00021 gray.4 GO:0005126 cytokine receptor binding 180 10 2.53 0.00022 gray.5 GO:0042379 chemokine receptor binding 41 5 0.58 0.00026 gray.6 GO:0023023 MHC protein complex binding 15 3 0.21 0.00110 gray.7 GO:0023026 MHC class II protein complex binding 15 3 0.21 0.00110 gray.8 GO:0005070 SH3/SH2 adaptor activity 41 4 0.58 0.00254 gray.9 GO:0019239 deaminase activity 20 3 0.28 0.00261 gray.10 GO:0004616 phosphogluconate dehydrogenase (decarbox... 6 2 0.08 0.00284 gray.11 GO:0016814 hydrolase activity, acting on carbon-nit... 23 3 0.32 0.00393 gray.12 GO:0032395 MHC class II receptor activity 7 2 0.1 0.00394 gray.13 GO:0044183 protein binding involved in protein fold... 7 2 0.1 0.00394 gray.14 GO:0051400 BH domain binding 7 2 0.1 0.00394 gray.15 GO:0005102 receptor binding 1037 25 14.58 0.00506 gray.16 GO:0005539 glycosaminoglycan binding 150 7 2.11 0.00521 gray.17 GO:0035591 signaling adaptor activity 54 4 0.76 0.00689 olivegreen.1 GO:0008236 serine-type peptidase activity 122 5 0.48 0.00010 olivegreen.2 GO:0017171 serine hydrolase activity 124 5 0.48 0.00011 olivegreen.3 GO:0050542 icosanoid binding 6 2 0.02 0.00022 olivegreen.4 GO:0050544 arachidonic acid binding 6 2 0.02 0.00022 olivegreen.5 GO:1901567 fatty acid derivative binding 6 2 0.02 0.00022 olivegreen.6 GO:0005125 cytokine activity 146 5 0.57 0.00024 olivegreen.7 GO:0050543 icosatetraenoic acid binding 7 2 0.03 0.00031 olivegreen.8 GO:0050786 RAGE receptor binding 8 2 0.03 0.00041 olivegreen.9 GO:0005126 cytokine receptor binding 180 5 0.7 0.00063 olivegreen.10 GO:0036041 long-chain fatty acid binding 10 2 0.04 0.00065 olivegreen.11 GO:0004252 serine-type endopeptidase activity 105 4 0.41 0.00071 olivegreen.12 GO:0042288 MHC class I protein binding 11 2 0.04 0.00080 olivegreen.13 GO:0008329 signaling pattern recognition receptor a... 15 2 0.06 0.00151 olivegreen.14 GO:0038187 pattern recognition receptor activity 15 2 0.06 0.00151 olivegreen.15 GO:0005102 receptor binding 1037 11 4.04 0.00159 olivegreen.16 GO:0005504 fatty acid binding 22 2 0.09 0.00326 olivegreen.17 GO:0070011 peptidase activity, acting on L-amino ac... 386 6 1.5 0.00355 olivegreen.18 GO:0004175 endopeptidase activity 267 5 1.04 0.00360 olivegreen.19 GO:0033754 indoleamine 2,3-dioxygenase activity 1 1 0 0.00390 olivegreen.20 GO:0008233 peptidase activity 400 6 1.56 0.00423 olivegreen.21 GO:0001664 G-protein coupled receptor binding 176 4 0.69 0.00473 olivegreen.22 GO:0008289 lipid binding 418 6 1.63 0.00524 olivegreen.23 GO:0005044 scavenger receptor activity 28 2 0.11 0.00525 olivegreen.24 GO:0004872 receptor activity 895 9 3.49 0.00652 olivegreen.25 GO:0004833 tryptophan 2,3-dioxygenase activity 2 1 0.01 0.00778 olivegreen.26 GO:0005133 interferon-gamma receptor binding 2 1 0.01 0.00778 olivegreen.27 GO:0023029 MHC class Ib protein binding 2 1 0.01 0.00778 olivegreen.28 GO:0032396 inhibitory MHC class I receptor activity 2 1 0.01 0.00778 olivegreen.29 GO:0008201 heparin binding 111 3 0.43 0.00910 orchid.1 GO:0001664 G-protein coupled receptor binding 176 6 0.77 0.00011 orchid.2 GO:0030246 carbohydrate binding 182 6 0.8 0.00013 orchid.3 GO:0008061 chitin binding 5 2 0.02 0.00019 orchid.4 GO:0004568 chitinase activity 6 2 0.03 0.00028 orchid.5 GO:0005125 cytokine activity 146 5 0.64 0.00042 orchid.6 GO:0046625 sphingolipid binding 11 2 0.05 0.00100 orchid.7 GO:0004872 receptor activity 895 11 3.91 0.00132 orchid.8 GO:0004888 transmembrane signaling receptor activit... 636 9 2.78 0.00149 orchid.9 GO:0008289 lipid binding 418 7 1.83 0.00208 orchid.10 GO:0004620 phospholipase activity 62 3 0.27 0.00247 orchid.11 GO:0004553 hydrolase activity, hydrolyzing O-glycos... 64 3 0.28 0.00270 orchid.12 GO:0004623 phospholipase A2 activity 18 2 0.08 0.00274 orchid.13 GO:0038023 signaling receptor activity 725 9 3.17 0.00364 orchid.14 GO:0052689 carboxylic ester hydrolase activity 72 3 0.31 0.00378 orchid.15 GO:0016298 lipase activity 74 3 0.32 0.00408 orchid.16 GO:0005504 fatty acid binding 22 2 0.1 0.00408 orchid.17 GO:0004498 calcidiol 1-monooxygenase activity 1 1 0 0.00437 orchid.18 GO:0008843 endochitinase activity 1 1 0 0.00437 orchid.19 GO:0031715 C5L2 anaphylatoxin chemotactic receptor ... 1 1 0 0.00437 orchid.20 GO:0031724 CXCR5 chemokine receptor binding 1 1 0 0.00437 orchid.21 GO:0035757 chemokine (C-C motif) ligand 19 binding 1 1 0 0.00437 orchid.22 GO:0035758 chemokine (C-C motif) ligand 21 binding 1 1 0 0.00437 orchid.23 GO:0038117 C-C motif chemokine 19 receptor activity 1 1 0 0.00437 orchid.24 GO:0038121 C-C motif chemokine 21 receptor activity 1 1 0 0.00437 orchid.25 GO:0047391 alkylglycerophosphoethanolamine phosphod... 1 1 0 0.00437 orchid.26 GO:0070524 11-beta-hydroxysteroid dehydrogenase (NA... 1 1 0 0.00437 orchid.27 GO:0016798 hydrolase activity, acting on glycosyl b... 85 3 0.37 0.00601 orchid.28 GO:0005126 cytokine receptor binding 180 4 0.79 0.00772 orchid.29 GO:0003796 lysozyme activity 2 1 0.01 0.00872 orchid.30 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NA... 2 1 0.01 0.00872 orchid.31 GO:0004667 prostaglandin-D synthase activity 2 1 0.01 0.00872 orchid.32 GO:0004917 interleukin-7 receptor activity 2 1 0.01 0.00872 orchid.33 GO:0031714 C5a anaphylatoxin chemotactic receptor b... 2 1 0.01 0.00872 orchid.34 GO:0045029 UDP-activated nucleotide receptor activi... 2 1 0.01 0.00872 skyblue.1 GO:0046872 metal ion binding 2625 17 7.23 0.00012 skyblue.2 GO:0019838 growth factor binding 97 4 0.27 0.00013 skyblue.3 GO:0043169 cation binding 2686 17 7.4 0.00016 skyblue.4 GO:0005509 calcium ion binding 502 7 1.38 0.00034 skyblue.5 GO:0046332 SMAD binding 60 3 0.17 0.00058 skyblue.6 GO:0005540 hyaluronic acid binding 18 2 0.05 0.00109 skyblue.7 GO:0005102 receptor binding 1037 9 2.86 0.00137 skyblue.8 GO:0043394 proteoglycan binding 24 2 0.07 0.00195 skyblue.9 GO:0033676 double-stranded DNA-dependent ATPase act... 1 1 0 0.00276 skyblue.10 GO:0008201 heparin binding 111 3 0.31 0.00342 skyblue.11 GO:0030674 protein binding, bridging 112 3 0.31 0.00351 skyblue.12 GO:0060090 binding, bridging 119 3 0.33 0.00416 skyblue.13 GO:0008237 metallopeptidase activity 128 3 0.35 0.00510 skyblue.14 GO:0008449 N-acetylglucosamine-6-sulfatase activity 2 1 0.01 0.00550 skyblue.15 GO:1901681 sulfur compound binding 147 3 0.41 0.00748 skyblue.16 GO:0008475 procollagen-lysine 5-dioxygenase activit... 3 1 0.01 0.00824 skyblue.17 GO:0071253 connexin binding 3 1 0.01 0.00824 skyblue.18 GO:0043167 ion binding 4046 18 11.15 0.00839 coral.1 GO:0030674 protein binding, bridging 112 3 0.11 0.00013 coral.2 GO:0060090 binding, bridging 119 3 0.11 0.00016 coral.3 GO:0097110 scaffold protein binding 30 2 0.03 0.00035 coral.4 GO:0008426 protein kinase C inhibitor activity 1 1 0 0.00095 coral.5 GO:1990254 keratin filament binding 2 1 0 0.00190 coral.6 GO:0019215 intermediate filament binding 7 1 0.01 0.00663