PhD thesis

Statistical Aspects of Forensic Genetics - Models for Qualitative and Quantitative STR Data

Public defence: Defended Friday November 5, 2010: Slides

Thesis (pdf): thesis.pdf (197 pages - 2.7 Mb).

Supplementary matrial

Chapter 2 Overdispersion in allelic counts and θ-correction in forensic genetics
DOI: 10.1016/j.tpb.2010.07.002
Link to dirmult on CRAN: http://cran.r-project.org/web/packages/dirmult
Higher resolution of Fig. 4 in Phillip et al., FSI:Gen (2010): Fig4.pdf.

Chapter 3 Analysis of matches and partial-matches in Danish DNA database
DOI: 10.1016/j.fsigen.2011.08.001 (To appear)
Link to animation of the correlation matrix of M, Σ(θ), for θ∈[0,1]: Animation (5.8 Mb).

Chapter 4 Evaluating the weight of evidence using quantitative STR data in DNA mixtures
DOI: 10.1111/j.1467-9876.2010.00722.x
Link to R-scripts fitting the parameters of the model using the EM-algorithm: EM.zip.

Chapter 5 Identifying contributors of DNA mixtures by means of quantitative information of STR typing
DOI: 10.1089/cmb.2010.0055
Link to the on-line implementation of the DNA mixture separating algorithm: Mixture separator
Link to R-package mixsep: mixsep (also available at the R-project's CRAN-portal: CRAN).

Chapter 6 Estimating the probability of allelic drop-out of STR alleles in forensic genetics
DOI: 10.1016/j.fsigen.2009.02.002.

Chapter 7 Sample and investigation specific filtering of quantitative data from STR DNA analysis
Link to additional QQ-plots: QQ-plots (3.7 Mb).

Chapter 7 Statistical model for degraded DNA samples and adjusted probabilities for allelic drop-out
DOI: 10.1016/j.fsigen.2011.03.001
Link to plots of degradation curves for the samples dicussed in the paper: Degradation curves (1.7 Mb).